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Moreover, one of a kind attributes inside the response profile of the test drug, which did not exist in the schooling list of drugs, will not be captured from the design. In contrast, dimensionality reduction solutions, including multidimensional scaling, look at distinctions involving all medicines and produce a low-dimensional Area that optimally

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(a) All information and facts submitted underneath this element has to be transmitted to FDA electronically in accordance with § 207.sixty one(a) Until FDA has granted a ask for for waiver of this necessity just before the date on which submission of these kinds of information is because of. Submission of the ask for for waiver won't justification

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